The Aivee Clinic, in partnership with Ardence Aesthetics has announced its new treatment PLINESTĀ®, the first and original injectable Polynucleotides treatment from Italy that improves overall skin health from within. āWe are excited for the approval of Plinest in the Philippines early this year, setting our first footprint in partnership with Aivee Clinic to extend the benefits of Plinest to more patientsā, shared by Ardence Aesthetic CEO, Mr. Yann Marche.

Photo: The Aivee Clinic | Aivee recognized as Top User in Southeast Asia (PLINESTĀ®) in 2024; (from left to right) Dr. Zāshen Teo, Dr. Aivee Aguilar-Teo of The Aivee Clinic; Sean Loo, Commercial Director of Ardence Aesthetics

Photo: The Aivee Clinic | Drs. Zāshen Teo and Dr. Aivee Aguilar Teo recognized as PLINESTĀ® Ambassadors 2024
This innovative injectable therapy features Polynucleotides (PN-HPTTM), a powerful DNA fragment extracted from freshwater-bred Italian trout fish gonads through a patented extraction and purification process known as HPTTM (Highly Purified Technology). This process was founded and patented by Mastelli, an Italian bio-pharmaceutical company, based on over 70 years of research.
The Product and Treatment Details
PLINESTĀ® Polynucleotides represent a significant advancement in non-invasive injectable treatments, and The Aivee Clinic the first to offer this treatment in the Philippines. Known for their regenerative capabilities, PLINESTĀ® is clinically proven to enhance skin health by:
- Reducing wrinkles and fine lines
- Repairing damaged skin tissue and revitalizing fibroblast and collagen
- Improving skin hydration and elasticity
- Enhancing skin tone and texture
- Minimizing pores, acne, and scars
PLINESTĀ® also offers anti-inflammatory and hydrating effects, resulting in healthier-looking and feeling skin.
Photo: The Aivee Clinic | Aivee Leaguers (from left to right) Vince Uy, Kylie Verzosa, Sam Pinto, Sean Loo of Ardence Aesthetics, Dr. Zāshen Teo and Dr. Aivee Aguilar-Teo of The Aivee Clinic, Yassi Pressman, Issa Pressman, Kyline Alcantara, Maika Rivera, and Janeena Chan
Patients can expect a variety of benefits from PLINEST® treatments, including a younger appearance, firmer skin, and tightening and lifting effects. The treatment is designed for individuals aged 20 to 40, targeting areas such as the face, décolleté, and hands.
āWhat really blew me away about this product is how it repairs and rejuvenates the skin. It is a very safe and effective product, and we have seen this with the glow on our patientsā faces.ā sharesĀ Dr. Z Teo, Co-founder and CEO of The Aivee Clinic.
A typical PLINESTĀ® treatment requires three sessions spaced four weeks apart, with follow-up sessions recommended every three to six months depending on the patientās skin condition. The effects of PLINESTĀ® can last up to six months, influenced by individual skin conditions, lifestyles, and environmental factors.
PLINESTĀ® can be safely combined with other aesthetic treatments such as laser, HIFU, fillers, and BOTOX. Clinical studies have demonstrated that PLINESTĀ® significantly enhances the outcomes of these treatments.
An Exclusive Launch for PLINESTĀ® In Manila
Photo: The Aivee Clinic | Dr. Siew Tuck Wah recognized as PLINESTĀ® Ambassador 2024 for Singapore with Sean Loo of Ardence Aesthetics
Photo: The Aivee Clinic | Dr. Aivee Aguilar-Teo recognized as PLINESTĀ® Ambassador 2024 with Sean Loo of Ardence Aesthetics
At the launch of PLINESTĀ® at Sala Bistro in Makati, guests were guided through an in-depth discussion of how the product offers a painless solution for those who want to reverse signs of aging and improve their skin health naturally by Dr. Siew Tuck Wah, Medical Director of Radium Medical Aesthetics in Singapore.Ā Ā
Dr. Siew mentioned, āPLINESTĀ® is a treatment which truly makes your skin younger, by inducing your skin cells to regenerate all components of the skin, restoring elasticity, skin glow, and smoothening the skin texture,ā he explains. āIt is suitable for improving almost any skin condition, including wrinkles, pigmentation, and skin sensitivity. TheĀ treatment is very safe, with minimal downtime unlike traditional skin boosters, and the results are very natural and visible.āĀ
“It rejuvenates my skin and makes it fresher,” shares Vicki Preysler, one of several featured Aivee Ambassadors at the event who each shared their positive experiences after receiving PLINESTĀ® at The Aivee Clinic.Ā Similarly, designer Vicki Narwani noted, “I’ve seen results in 3 sessions, and it all looks natural.”Ā
Photo: The Aivee Clinic | Aivee Leaguers from left to right (Vince Uy, Sam Pinto, Yassi Pressman, Maricel Soriano, Kylie Verzosa, Dr. Aivee Aguilar-Teo, Dr. Zāshen Teo, Keli Teo, Kyline Alcantara, Issa Pressman, Maika Rivera, Janeena Chan
During the event, the Aivee Clinic was also honored as the PLINESTĀ® Ambassador for the Philippines, being the first clinic in the country to offer this innovative treatment.
To learn more about PLINESTĀ®, visit theaiveeclinic.com.